1. If you want to disable a vendor from EzyPO but still have them accessible in Eclipse you will need to edit the vendor details from Vendor Master Maintenance.
Go to Vendor Master Maintenance -> Vendor Details -> Vendor Warnings -> and tick "Exclude vendor from EzyPO"
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To edit multiple vendors at once, you can export the vendors to Excel and then change the Exclude from EzyPO/DPF flag to Y.
See: Export Vendors Information / Editing Vendors in Bulk
2. Alternatively, marking a vendor as inactive inside Eclipse will disable them in both Eclipse and EzyPO.
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3. If you do not have access to Eclipse, you can do this inside EzyPO by following these instructions here: Editing EzyPO Vendors via Excel
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