1. If you want to disable a vendor from EzyPO but still have them accessible in Eclipse you will need to edit the vendor details from Vendor Master Maintenance.
Go to Vendor Master Maintenance -> Vendor Details -> Vendor Warnings -> and tick "Exclude vendor from EzyPO"
2. Alternatively, marking a vendor as inactive inside Eclipse will disable them in both Eclipse and EzyPO.
3. If you do not have access to Eclipse, you can do this inside EzyPO by following these instructions here: Editing EzyPO Vendors via Excel